Microdose THC

Why Microdose? Benefits of Microdose Gummies for Wellness

Written by: Jaime Alefosio

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Published on

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Time to read 5 min


The endocannabinoid system (ECS) plays a crucial role in maintaining homeostasis within the body, regulating a wide range of physiological processes, including pain sensation, immune response, mood, appetite, and memory. What most people don't know is that the ECS can become overstimulated with traditional size doses, This is where  Microdose THC comes in.  Cannabinoids from the Hemp plant, like THC and CBD, interact with the ECS by binding to its receptors (CB1 and CB2), mimicking the action of endocannabinoids—cannabinoid-like substances produced naturally by the human body.

What are Microdose Gummies?

At Hey Mary Jane our Microdose Gummies are carefully formulated edibles that deliver a precise low dose of THC, often paired with other supportive ingredients like CBD, adaptogens, or nootropics. Unlike traditional edibles, which are designed for stronger effects, Microdose Gummies focus on delivering gentle, balanced benefits that you can take throughout the day.

These gummies are perfect for those looking to microdose THC for wellness, productivity, or relaxation.

Key Ingredients in Microdose THC Gummies

  • THC : Provides subtle mood-boosting, calming, and anti-stress effects.
  • CBD : Balances THC’s effects and reduces potential feelings of overwhelm.
  • Adaptogens : Natural herbs like Turmeric or Cordyceps to enhance resilience against stress.
  • Nootropics : Ingredients like L-Theanine or Lion’s Mane that promote focus and mental clarity.

How Microdose Gummies Differ from Full-Dose Edibles

  • Microdose Gummies : Deliver subtle euphoric effects, ideal for use throughout the day
  • Full-Dose Edibles : Designed for stronger, often psychoactive effects.
    With Microdose Gummies , you can enjoy THC’s benefits without feeling stoned, making them perfect for daily use.

Benefits of Microdosing THC and Microdose Gummies 

Daily microdosing of cannabinoids can potentially benefit the body and its maintenance of homeostasis in several ways:

Subtle Modulation of the ECS:

Unlike large doses of cannabinoids, which can overwhelm the ECS and lead to pronounced psychoactive effects and potential side effects, microdosing works by providing a gentle, consistent stimulation of the ECS. This can help support the system's natural functions without causing disruptive imbalances. All of Hey Mary Janes Gummies are made with a subtle microdose of cannabinoids to help balance the body.

Enhanced Endocannabinoid Tone:

Regular, low-level stimulation of the ECS through microdosing may help improve the "tone" of the endocannabinoid system, enhancing its responsiveness and efficiency. An improved ECS tone means better regulation of homeostasis across various bodily systems. 

Reduced Risk of Desensitization:

High doses of cannabinoids can lead to receptor desensitization or downregulation, where the body reduces the number of receptors or their responsiveness to maintain balance in response to excessive stimulation. Microdosing THC helps avoid this issue by keeping the stimulation level low and within a range that supports the ECS without overwhelming it.

Support for Neurogenesis and Neuroprotection:

Some research suggests that cannabinoids may promote neurogenesis (the growth of new neurons) and offer neuroprotective effects. Microdosing may help harness these benefits without the potential negative impacts on cognitive function that can come with higher doses. 

Microdosing THC for Stress and Anxiety Relief:

By modulating the ECS, microdosing cannabinoids with our Hey Mary Jane gummies can potentially improve the body's resilience to stress. The ECS is involved in regulating the stress response, and by supporting its function, microdosing may help maintain a more balanced emotional state.

Microdose THC May Reduce Pain and Inflammation :

The ECS is deeply involved in the regulation of pain and inflammation. Microdosing cannabinoids can provide a way to influence these processes subtly, potentially offering relief from chronic pain and inflammatory conditions without the side effects  associated with conventional pain medications or high doses of cannabinoids. With Tumeric, Full spectrum CBD and CBG,   Our Soothe CBG Gummies offer a natural alternative to your current daily go to . 

Better Sleep with Microdose Gummies:

Cannabinoids have been shown to influence sleep. Through its action on the ECS, microdosing might help stabilize sleep patterns , contributing to better overall homeostasis by ensuring adequate rest and recovery. Our Drift CBN Sleep Gummiesare the perfect combination of a subtle microdose of cannabinoids , valerian root, magnesium and other sleep including herbs to help you drift off to dreamland.

It's important to note that while the theoretical benefits of microdosing cannabinoids in relation to the ECS and homeostasis are compelling, research in this area is still developing. Many of the insights into how cannabinoids interact with the ECS come from studies involving higher doses. As such, the specific effects and benefits of microdosing need further investigation to be fully understood. Nonetheless, speaking from personal experience, the microdose approach allows for a more subtle enjoyable experience for everyday use when you need a boost or to take the "edge" off. The practice of microdosing holds promise as an approach to leveraging the therapeutic potentials of cannabinoids while minimizing risks and side effects.

How to Start with Microdose THC Gummies

If you’re new to microdosing, starting small is key. Here’s a quick guide:

  1. Start Low : Begin with a 1-2mg dose of THC.
  2. Be Consistent : Take Microdose Gummies daily at the same time for cumulative benefits.
  3. Listen to Your Body : Track how you feel and adjust the dose gradually.

Remember, the goal of microdosing is to feel balanced—not “high.”

How Long Do Microdose Gummies Take to Work?

Our Microdose Gummies typically take 20-30 minutes to kick in. Factors like metabolism, tolerance, and empty stomachs can affect onset time.

Can I Use Microdose Gummies Daily?

Yes, Microdose Gummies are designed for daily use. Their low-dose formula makes them ideal for ongoing wellness benefits without strong psychoactive effects.

What’s the Difference Between Microdose THC and Full-Dose THC?

Microdose THC delivers subtle therapeutic effects (1-5mg), while full-dose THC (10mg+) produces stronger psychoactive results. Microdosing is ideal for people looking to integrate THC into their routine without disrupting daily activities.

Microdose Gummies -Jaimes Take

Jaime Alefosio BCEHC

Jaime Alefosio is an entrepreneur and wellness advocate, best known as the founder of Hey Mary Jane (HMJ), a company specializing in microdose gummies that combine functional supplements with cannabinoids to promote holistic health. Her journey into wellness was profoundly influenced by personal health challenges, including undiagnosed Lyme disease, which led her to explore alternative healing methods. Through this exploration, she developed a passion for natural medicine and the therapeutic potential of cannabis. This passion culminated in the creation of HMJ, where she serves as Chief Visionary Officer, aiming to provide effective, discreet wellness solutions.

Jaime's commitment to wellness and innovation has garnered industry recognition. In 2024, HMJ was acknowledged for producing some of the best THCV and CBG gummies, highlighting the company's unique approach of integrating functional supplements with cannabinoids.Now a Board Certified Exponential Health Coach, Jaime continues to advocate for natural healing and the benefits of cannabis, aiming to empower individuals on their wellness journeys.

How it All Began